Can telomere shortening explain sigmoidal growth curves?
نویسندگان
چکیده
منابع مشابه
Can telomere shortening explain sigmoidal growth curves?
A general branching process model is proposed to describe the shortening of telomeres in eukaryotic chromosomes. The model is flexible and incorporates many special cases to be found in the literature. In particular, we show how telomere shortening can give rise to sigmoidal growth curves, an idea first expressed by Portugal et al. [A computational model for telomere-dependent cell-replicative ...
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ژورنال
عنوان ژورنال: Journal of Biological Dynamics
سال: 2010
ISSN: 1751-3758,1751-3766
DOI: 10.1080/17513750903377442